Comorbid Conditions
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  • Addiction in Patients With Chronic Pain Addiction in Patients With Chronic Pain
    Michael R. Clark, MD, MPH, MBA, Joyce King, MD, and Glenn J. Treisman, MD, PhD

    Some fraction of opioid-treated patients with chronic pain will engage in aberrant substance use, including compulsive drug seeking and addiction.

  • Psychiatric Issues in Chronic Pain Psychiatric Issues in Chronic Pain
    Michael R. Clark, MD, MPH, MBA

    An individual’s perception and experience of chronic pain result from complex interplay among multiple biological, psychological, and social factors.

  • Chronic Pain and Psychiatric Symptoms Chronic Pain and Psychiatric Symptoms
    Michael R. Clark, MD, MPH, MBA, Joyce King, MD, and Glenn J. Treisman, MD, PhD

    Chronic pain is often comorbid with affective symptomatology.

  • Cognitive-Behavioral Therapy for Sleep Abnormalities of Chronic Pain Patients Cognitive-Behavioral Therapy for Sleep Abnormalities of Chronic Pain Patients
    Nicole K. Y. Tang, DPhil

    Chronic pain is a biopsychosocial condition that adversely affects multiple domains, including sleep. In fact, most chronic pain patients report fragmented or poor quality sleep. Moreover, studies suggest that pain onset often precedes the development of clinical insomnia, and pain intensity correlates with the degree of sleep disturbance.

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Section Editor
Srinivas R. Nalamachu, MD
User Activity
Srinivas R. Nalamachu, MD

President and Medical Director
International Clinical Research Institute, Inc.
Co-Director
Pain Management Institute
Overland Park, Kansas

View AllPublications
Chronic opioid therapy and preventive services in rural primary care: an Oregon rural practice-based research network study.
Buckley DI, Calvert JF, Lapidus JA, et al.
Ann Fam Med. 2010;8(3):237-44.
PURPOSE:...

A different kind of co-morbidity: Understanding posttraumatic stress disorder and chronic pain
Beck JG, Clapp JD.
Psychol Trauma. 2011 Jun;3(2):101-108.
Many traumatic events leave...

Chronic low back pain, sleep disturbance, and interleukin-6.
Heffner KL, France CR, Trost Z. et al.
Clin J Pain. 2011 Jan;27(1):35-41.
OBJECTIVES:...

Cognitive-behavioral therapy for sleep abnormalities of chronic pain patients.
Tang NK.
Curr Rheumatol Rep. 2009 Dec;11(6):451-60.
Chronic pain and insomnia often...

Effect of telecare management on pain and depression in patients with cancer: a randomized trial.
Kroenke K, Theobald D, Wu J et al.
JAMA. 2010 Jul 14;304(2):163-71.
CONTEXT: Pain and...