Neuromodulation in Special Populations: Examining the Efficacy of Stimulation Versus Intrathecal Pump Therapy
Salim M. Hayek, MD, PhD
Certain patient populations with refractory chronic pain pose particular challenges when considering neuromodulation.
The Pain Assessment and Documentation Tool
Steven D. Passik, PhD
Clinical trial evidence, expert opinion, and recommendations in clinical practice guidelines support long-term opioid therapy in appropriately selected and monitored patients with chronic nonmalignant pain.
Using Tools to Risk Stratify Patients for Long-term Opioid Therapy
Howard S. Smith, MD
Standard of care requires that patients being considered for long-term opioid therapy are assessed for the risk of medication misuse and abuse.
MRI Analysis of the Lumbar Spine: Can It Predict Response to Diagnostic and Therapeutic Facet Procedures?
Milan P. Stojanovic, MD
Current diagnostic techniques often fail to identify pain generators in patients with low back pain.
A Theoretical Role for the Genomic Oxidative-Reductive Balance in the Development of Complex Regional Pain Syndrome
Howard S. Smith, MD
The endogenous antioxidant system consists of a number of proteins (eg, antioxidant enzymes) and small molecules that maintain the reducing environment of the body and prevent potentially damaging reactions initiated by reactive oxygen species.
A Nonsurgical Approach to the Management of Patients with Lumbar Radiculopathy Secondary to Herniated Disk: A Prospective Observational Cohort Study with Follow-up
Donald R. Murphy, DC
Lumbar radiculopathy secondary to a herniated disk is a prevalent problem, affecting as many as 1 in 3 men and almost 1 in 2 women at some point in their lifetimes.
How Does Your Pain Practice Measure Up? Lessons Learned from Commercial Insurance Claims Data
Steven Delaronde, MPH, MSW
Rates of lumbosacral and cervical injections for the treatment of patients with musculoskeletal pain have increased significantly over the last decade, despite at times conflicting evidence regarding their efficacy.
Hippocampal correlates of pain in healthy elderly adults: A pilot study
Molly E. Zimmerman, PhD
Previous imaging studies of patients with chronic pain have identified abnormalities in the thalamus, prefrontal cortex, cingulate, and somatosensory cortex, each of which is involved in nociceptive processing.
Peripheral Nerve Stimulation: What Are the Current Indications and Which Patients Are Candidates?
Konstantin V. Slavin, MD
Peripheral nerve stimulation is a neuromodulation technique in which electrical current is applied to peripheral nerves to treat various neuropathic pain conditions.
Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings
Roger B. Fillingim, PhD
The effects of sex and gender on the subjective experience of pain and analgesic response have generated marked scientific and clinical interest over the last decade. Women are at greater risk for many painful conditions and are more sensitive to experimentally induced pain.
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